Wait for green, then click as quickly as you can.
About reaction time
Most people usually react to a simple visual signal in about 200 to 250 milliseconds, but it can be slower if they are tired, distracted, or not expecting the signal. Some people get below 200 ms, while others may stay above 300 ms.
This tester measures the time between the moment the box turns green and the moment you click. That time includes your eyes noticing the color change, your brain understanding what happened, and your hand moving the mouse and pressing the button.
Reaction time is not the same thing as full thinking speed. It is more like a chain: see the signal, process it, move your muscles, and finish the action. Even internet browser delays and device speed can change the final number a little bit.
People often do better after a few tries because they learn the rhythm of the test, but if they click too early that means they guessed instead of reacting. Sleep, caffeine, focus, stress, screen refresh rate, and mouse feel can all change your score.
Athletes, gamers, and drivers care about reaction time because quick responses help in real situations, but having a low number here does not automatically mean someone is better at every skill. It only measures one small part of human reflex.